Commit 3e311caf authored by wangys_biolab's avatar wangys_biolab

Update README.md

parent 9de5d340
......@@ -53,46 +53,34 @@ Before running Effector-GAN, users should make sure all the following packages a
pip3 install sklearn
##**Effector-GAN**
## **Effector-GAN**
git clone git@github.com:Wangys-prog/prPred.git
**Add prPred into into environment variables**
**(./prPred/dist/prPred)**
` export PATH=$PATH:/xxxx/xxxx/xxxx/prPred/dist/prPred`
`git clone git@github.com:Wangys-prog/prPred.git`
## Input parameters
prPred -h
$ -i inputfile in FASTA format
$ -o output folder
Effector-GAN.py -h
$ -i inputfile in FASTA format
$ -o output folder
### usage
`prPred -i /xxxx/xxxx/test/test.fasta -o result `
**or**
**Using absolute path to invoke prPred.py (/xxxx/xxxx/prPred/prPred.py)**
` python xxxx/xxxx/prPred/prPred.py -i /xxxx/xxxx/test/test.fasta -o /xxxx/xxxxx/result `
###**Output file**
> domain_result
> R_protein_possibility.fasta
`Effector-GAN.py -i test.fasta -o test_result.csv `
`
## WGAN.py
Synthetic protein feature samples based on generative adversarial networks
Synthetic protein feature samples based on generative adversarial networks
## CTST2.py
Effector-GAN uses the leave-one-out cross-validation (LOOCV) method based on K nearest neighbor algorithm (KNN; K=1) classifier to evaluate the optimal synthetic protein feature samples, which are used to augment the original positive training samples
Effector-GAN uses the leave-one-out cross-validation (LOOCV) method based on K nearest neighbor algorithm (KNN; K=1) classifier to evaluate the optimal synthetic protein feature samples, which are used to augment the original positive training samples
## figure_tsne.py
t-SNE-transformed 2D visualization of real and synthetic protein feature samples obtained from different training iterations
## **If you use prPred, please cite:**
(1) Wang Y, Wang P, Guo Y, et al. prPred: A Predictor to Identify Plant Resistance Proteins by Incorporating k-Spaced Amino Acid (Group) Pairs[J]. Frontiers in bioengineering and biotechnology, 2021, 8: 1593.
(1) Wang Y, .Effector-GAN: prediction of fungal effector proteins based on pre-trained deep representation learning methods and generative adversarial networks
(2) Yansu Wang, Murong Zhou, Quan Zou, Lei Xu. Machine learning for phytopathology: from the molecular scale towards the network scale. Briefings in Bioinformatics. 2021, Doi: 10.1093/bib/bbab037
(3) Yansu Wang, Lei Xu, Quan Zou, Chen Lin. prPred-DRLF: plant R protein predictor using deep representation learning features. Proteomics. 2021. DOI: 10.1002/pmic.202100161
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